Infiltration: Adrenal infiltration occurs in hemochromatosis, amyloidosis, and metastases. This is more common in children and patients with asplenia. An Adrenal crisis due to meningococcemia is known as the Waterhouse-Friderichsen syndrome. Blastomycosis is a common cause in South America.Īdrenal Hemorrhage: Bilateral adrenal hemorrhages can be precipitated by DIC, trauma, meningococcemia, neoplastic processes. Other infectious causes include disseminated fungal infections, histoplasmosis, and syphilis. The prevalence of tuberculosis has declined, but HIV has emerged as the most important cause of adrenal insufficiency associated with adrenal necrosis. Infections: This includes sepsis, tuberculosis, cytomegalovirus, and HIV. Addison disease has been reported with celiac disease.
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